Found 7 hits of ki for monomerid = 50231596 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113907
BindingDB Entry DOI: 10.7270/Q20K2DJC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Advinus Therapeutics Ltd.
Curated by ChEMBL
| Assay Description
Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated... |
Bioorg Med Chem 25: 1963-1975 (2017)
Article DOI: 10.1016/j.bmc.2017.02.029
BindingDB Entry DOI: 10.7270/Q2KH0QKC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113907
BindingDB Entry DOI: 10.7270/Q20K2DJC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Advinus Therapeutics Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 mins |
Bioorg Med Chem 25: 1963-1975 (2017)
Article DOI: 10.1016/j.bmc.2017.02.029
BindingDB Entry DOI: 10.7270/Q2KH0QKC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2b
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Advinus Therapeutics Ltd.
Curated by ChEMBL
| Assay Description
Antagonist activity at human adenosine A2B receptor expressed in HEK293 cells assessed as reduction in NECA-induced increase in cAMP level preincubat... |
Bioorg Med Chem 25: 1963-1975 (2017)
Article DOI: 10.1016/j.bmc.2017.02.029
BindingDB Entry DOI: 10.7270/Q2KH0QKC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2b
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Advinus Therapeutics Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]MRS-1754 from human adenosine A2B receptor expressed in HEK293 cell membranes after 90 mins |
Bioorg Med Chem 25: 1963-1975 (2017)
Article DOI: 10.1016/j.bmc.2017.02.029
BindingDB Entry DOI: 10.7270/Q2KH0QKC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a
(Homo sapiens (Human)) | BDBM50231596
(CHEMBL4074150)Show SMILES CCCn1c(Oc2ccc(F)c(F)c2)nc2nc([nH]c2c1=O)C1CCCC1 Show InChI InChI=1S/C19H20F2N4O2/c1-2-9-25-18(26)15-17(23-16(22-15)11-5-3-4-6-11)24-19(25)27-12-7-8-13(20)14(21)10-12/h7-8,10-11H,2-6,9H2,1H3,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Advinus Therapeutics Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membranes after 90 mins |
Bioorg Med Chem 25: 1963-1975 (2017)
Article DOI: 10.1016/j.bmc.2017.02.029
BindingDB Entry DOI: 10.7270/Q2KH0QKC |
More data for this
Ligand-Target Pair | |
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