BindingDB PrimarySearch

Found 11 hits of ki for monomerid = 50236140
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human cloned CA2 by CO2 hydration method				J Med Chem 51: 1945-53 (2008) Article DOI: 10.1021/jm701426t BindingDB Entry DOI: 10.7270/Q28P61CM
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human CA9 catalytic domain by CO2 hydration method				J Med Chem 51: 1945-53 (2008) Article DOI: 10.1021/jm701426t BindingDB Entry DOI: 10.7270/Q28P61CM
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assay				J Med Chem 56: 9623-34 (2013) Article DOI: 10.1021/jm401163e BindingDB Entry DOI: 10.7270/Q2XK8JGS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydration assay				J Med Chem 56: 9623-34 (2013) Article DOI: 10.1021/jm401163e BindingDB Entry DOI: 10.7270/Q2XK8JGS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars		55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (docked)
Carbonic anhydrase 14 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay				J Med Chem 56: 9623-34 (2013) Article DOI: 10.1021/jm401163e BindingDB Entry DOI: 10.7270/Q2XK8JGS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay				J Med Chem 56: 9623-34 (2013) Article DOI: 10.1021/jm401163e BindingDB Entry DOI: 10.7270/Q2XK8JGS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human cloned CA1 by CO2 hydration method				J Med Chem 51: 1945-53 (2008) Article DOI: 10.1021/jm701426t BindingDB Entry DOI: 10.7270/Q28P61CM
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assay				J Med Chem 56: 9623-34 (2013) Article DOI: 10.1021/jm401163e BindingDB Entry DOI: 10.7270/Q2XK8JGS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50236140 (4-ethynyl benzene sulfonamide \| 4-ethynylbenzenesu...) Show SMILES NS(=O)(=O)c1ccc(cc1)C#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...				J Med Chem 62: 7233-7249 (2019) Article DOI: 10.1021/acs.jmedchem.9b00845 BindingDB Entry DOI: 10.7270/Q2D79FRD
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair