new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits of ki for monomerid = 50293676   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))
BDBM50293676
PNG
(2-(2-chlorophenylthio)-N-(5-methyl-1H-pyrazol-3-yl...)
Show SMILES Cc1cc(Nc2nc(Sc3ccccc3Cl)nc3ccccc23)[nH]n1
Show InChI InChI=1S/C18H14ClN5S/c1-11-10-16(24-23-11)21-17-12-6-2-4-8-14(12)20-18(22-17)25-15-9-5-3-7-13(15)19/h2-10H,1H3,(H2,20,21,22,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
5n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL


Assay Description
Inhibition of Aurora-A by coupled assay


Bioorg Med Chem Lett 19: 3586-92 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.136
BindingDB Entry DOI: 10.7270/Q28K7944
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50293676
PNG
(2-(2-chlorophenylthio)-N-(5-methyl-1H-pyrazol-3-yl...)
Show SMILES Cc1cc(Nc2nc(Sc3ccccc3Cl)nc3ccccc23)[nH]n1
Show InChI InChI=1S/C18H14ClN5S/c1-11-10-16(24-23-11)21-17-12-6-2-4-8-14(12)20-18(22-17)25-15-9-5-3-7-13(15)19/h2-10H,1H3,(H2,20,21,22,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
126n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL


Assay Description
Inhibition of GSK3-beta


Bioorg Med Chem Lett 19: 3586-92 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.136
BindingDB Entry DOI: 10.7270/Q28K7944
More data for this
Ligand-Target Pair
Aurora kinase B


(Homo sapiens (Human))
BDBM50293676
PNG
(2-(2-chlorophenylthio)-N-(5-methyl-1H-pyrazol-3-yl...)
Show SMILES Cc1cc(Nc2nc(Sc3ccccc3Cl)nc3ccccc23)[nH]n1
Show InChI InChI=1S/C18H14ClN5S/c1-11-10-16(24-23-11)21-17-12-6-2-4-8-14(12)20-18(22-17)25-15-9-5-3-7-13(15)19/h2-10H,1H3,(H2,20,21,22,23,24)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
445n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL


Assay Description
Inhibition of Aurora-B


Bioorg Med Chem Lett 19: 3586-92 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.136
BindingDB Entry DOI: 10.7270/Q28K7944
More data for this
Ligand-Target Pair