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Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 50310937   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA-A receptor; alpha-5/beta-3/gamma-2


(Homo sapiens (Human))
BDBM50310937
PNG
(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Show SMILES Cc1noc(Cc2nc3-c4cc(Br)ccc4-n4cnc(C)c4Cn3n2)n1
Show InChI InChI=1S/C17H14BrN7O/c1-9-14-7-25-17(21-15(22-25)6-16-20-10(2)23-26-16)12-5-11(18)3-4-13(12)24(14)8-19-9/h3-5,8H,6-7H2,1-2H3
PDB

KEGG

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Article
PubMed
0.900n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptor


Bioorg Med Chem Lett 19: 5958-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.027
BindingDB Entry DOI: 10.7270/Q2R78FBR
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))
BDBM50310937
PNG
(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Show SMILES Cc1noc(Cc2nc3-c4cc(Br)ccc4-n4cnc(C)c4Cn3n2)n1
Show InChI InChI=1S/C17H14BrN7O/c1-9-14-7-25-17(21-15(22-25)6-16-20-10(2)23-26-16)12-5-11(18)3-4-13(12)24(14)8-19-9/h3-5,8H,6-7H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
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CHEMBL
PC cid
PC sid
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Article
PubMed
277n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptor


Bioorg Med Chem Lett 19: 5958-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.027
BindingDB Entry DOI: 10.7270/Q2R78FBR
More data for this
Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2


(Homo sapiens (Human))
BDBM50310937
PNG
(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Show SMILES Cc1noc(Cc2nc3-c4cc(Br)ccc4-n4cnc(C)c4Cn3n2)n1
Show InChI InChI=1S/C17H14BrN7O/c1-9-14-7-25-17(21-15(22-25)6-16-20-10(2)23-26-16)12-5-11(18)3-4-13(12)24(14)8-19-9/h3-5,8H,6-7H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
317n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptor


Bioorg Med Chem Lett 19: 5958-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.027
BindingDB Entry DOI: 10.7270/Q2R78FBR
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2


(Homo sapiens (Human))
BDBM50310937
PNG
(5-((3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,...)
Show SMILES Cc1noc(Cc2nc3-c4cc(Br)ccc4-n4cnc(C)c4Cn3n2)n1
Show InChI InChI=1S/C17H14BrN7O/c1-9-14-7-25-17(21-15(22-25)6-16-20-10(2)23-26-16)12-5-11(18)3-4-13(12)24(14)8-19-9/h3-5,8H,6-7H2,1-2H3
UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
469n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptor


Bioorg Med Chem Lett 19: 5958-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.027
BindingDB Entry DOI: 10.7270/Q2R78FBR
More data for this
Ligand-Target Pair