Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NADPH oxidase 4 (Homo sapiens (Human)) | BDBM50330721 (4-((2-(2-chlorophenyl)-4-methyl-3,6-dioxo-2,3-dihy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 259 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex, S.A. Curated by ChEMBL | Assay Description Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH | J Med Chem 53: 7715-30 (2010) Article DOI: 10.1021/jm100773e BindingDB Entry DOI: 10.7270/Q2KH0NKJ | |||||||||||
More data for this Ligand-Target Pair |