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Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 50360158   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Mus musculus (Mouse))
BDBM50360158
PNG
(CHEMBL1929551)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO3S2/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(26)22(18)11-13-27-12-3-6-21(24)25/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,24,25)/b9-7+/t18-,19+/m0/s1
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0.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))
BDBM50360158
PNG
(CHEMBL1929551)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO3S2/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(26)22(18)11-13-27-12-3-6-21(24)25/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,24,25)/b9-7+/t18-,19+/m0/s1
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980n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))
BDBM50360158
PNG
(CHEMBL1929551)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO3S2/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(26)22(18)11-13-27-12-3-6-21(24)25/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,24,25)/b9-7+/t18-,19+/m0/s1
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1.70E+3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Mus musculus (Mouse))
BDBM50360158
PNG
(CHEMBL1929551)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO3S2/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(26)22(18)11-13-27-12-3-6-21(24)25/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,24,25)/b9-7+/t18-,19+/m0/s1
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2.80E+3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair