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Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 50360161   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Mus musculus (Mouse))
BDBM50360161
PNG
(CHEMBL1929528)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)[C@@H]2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H32O5S/c1-28-16-18-5-2-4-17(14-18)15-20(24)9-7-19-8-10-22(25)21(19)11-13-29-12-3-6-23(26)27/h2,4-5,7,9,14,19-21,24H,3,6,8,10-13,15-16H2,1H3,(H,26,27)/b9-7+/t19-,20+,21+/m0/s1
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PubMed
2.40n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))
BDBM50360161
PNG
(CHEMBL1929528)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)[C@@H]2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H32O5S/c1-28-16-18-5-2-4-17(14-18)15-20(24)9-7-19-8-10-22(25)21(19)11-13-29-12-3-6-23(26)27/h2,4-5,7,9,14,19-21,24H,3,6,8,10-13,15-16H2,1H3,(H,26,27)/b9-7+/t19-,20+,21+/m0/s1
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PubMed
190n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))
BDBM50360161
PNG
(CHEMBL1929528)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)[C@@H]2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H32O5S/c1-28-16-18-5-2-4-17(14-18)15-20(24)9-7-19-8-10-22(25)21(19)11-13-29-12-3-6-23(26)27/h2,4-5,7,9,14,19-21,24H,3,6,8,10-13,15-16H2,1H3,(H,26,27)/b9-7+/t19-,20+,21+/m0/s1
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PubMed
470n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Mus musculus (Mouse))
BDBM50360161
PNG
(CHEMBL1929528)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)[C@@H]2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H32O5S/c1-28-16-18-5-2-4-17(14-18)15-20(24)9-7-19-8-10-22(25)21(19)11-13-29-12-3-6-23(26)27/h2,4-5,7,9,14,19-21,24H,3,6,8,10-13,15-16H2,1H3,(H,26,27)/b9-7+/t19-,20+,21+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair