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Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 50360163   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Mus musculus (Mouse))
BDBM50360163
PNG
(CHEMBL1929530)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C20H27NO5S/c1-15-4-2-5-16(12-15)13-18(22)8-7-17-14-26-20(25)21(17)9-11-27-10-3-6-19(23)24/h2,4-5,7-8,12,17-18,22H,3,6,9-11,13-14H2,1H3,(H,23,24)/b8-7+/t17-,18+/m0/s1
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PubMed
2.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Mus musculus (Mouse))
BDBM50360163
PNG
(CHEMBL1929530)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C20H27NO5S/c1-15-4-2-5-16(12-15)13-18(22)8-7-17-14-26-20(25)21(17)9-11-27-10-3-6-19(23)24/h2,4-5,7-8,12,17-18,22H,3,6,9-11,13-14H2,1H3,(H,23,24)/b8-7+/t17-,18+/m0/s1
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Article
PubMed
2.80E+3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Mus musculus (Mouse))
BDBM50360163
PNG
(CHEMBL1929530)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C20H27NO5S/c1-15-4-2-5-16(12-15)13-18(22)8-7-17-14-26-20(25)21(17)9-11-27-10-3-6-19(23)24/h2,4-5,7-8,12,17-18,22H,3,6,9-11,13-14H2,1H3,(H,23,24)/b8-7+/t17-,18+/m0/s1
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PubMed
4.40E+3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Mus musculus (Mouse))
BDBM50360163
PNG
(CHEMBL1929530)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C20H27NO5S/c1-15-4-2-5-16(12-15)13-18(22)8-7-17-14-26-20(25)21(17)9-11-27-10-3-6-19(23)24/h2,4-5,7-8,12,17-18,22H,3,6,9-11,13-14H2,1H3,(H,23,24)/b8-7+/t17-,18+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair