Found 2 hits of ki for monomerid = 50369309 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50369309
(CHEMBL2369626)Show SMILES C[C@@H](O[C@H]1O[C@@H](COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(N)=O Show InChI InChI=1S/C57H73N9O20/c1-29(62-52(76)40(58)23-36-14-18-38(71)19-15-36)51(75)64-41(24-35-11-8-7-9-12-35)53(77)61-27-46(74)63-42(25-37-16-20-39(72)21-17-37)56(80)66-22-10-13-43(66)54(78)65-47(55(79)60-26-45(59)73)30(2)82-57-50(85-34(6)70)49(84-33(5)69)48(83-32(4)68)44(86-57)28-81-31(3)67/h7-9,11-12,14-21,29-30,40-44,47-50,57,71-72H,10,13,22-28,58H2,1-6H3,(H2,59,73)(H,60,79)(H,61,77)(H,62,76)(H,63,74)(H,64,75)(H,65,78)/t29-,30-,40+,41+,42+,43+,44+,47+,48+,49-,50+,57+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara
Curated by ChEMBL
| Assay Description Opioid receptor mu 1 binding affinity by displacement of radioligand [3H][DAla,MePhe,Gly-ol]enkephalin (DAGO) from rat brain membrane synaptosomes |
J Med Chem 40: 2948-52 (1997)
Article DOI: 10.1021/jm970119r BindingDB Entry DOI: 10.7270/Q2BC406Q |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50369309
(CHEMBL2369626)Show SMILES C[C@@H](O[C@H]1O[C@@H](COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(N)=O Show InChI InChI=1S/C57H73N9O20/c1-29(62-52(76)40(58)23-36-14-18-38(71)19-15-36)51(75)64-41(24-35-11-8-7-9-12-35)53(77)61-27-46(74)63-42(25-37-16-20-39(72)21-17-37)56(80)66-22-10-13-43(66)54(78)65-47(55(79)60-26-45(59)73)30(2)82-57-50(85-34(6)70)49(84-33(5)69)48(83-32(4)68)44(86-57)28-81-31(3)67/h7-9,11-12,14-21,29-30,40-44,47-50,57,71-72H,10,13,22-28,58H2,1-6H3,(H2,59,73)(H,60,79)(H,61,77)(H,62,76)(H,63,74)(H,64,75)(H,65,78)/t29-,30-,40+,41+,42+,43+,44+,47+,48+,49-,50+,57+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 87 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara
Curated by ChEMBL
| Assay Description Opioid receptor delta 1 binding affinity by displacement of radioligand [3H][D-Pen]-enkephalin (DPDPE) from rat brain membrane synaptosomes |
J Med Chem 40: 2948-52 (1997)
Article DOI: 10.1021/jm970119r BindingDB Entry DOI: 10.7270/Q2BC406Q |
More data for this Ligand-Target Pair | |