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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50371522   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NPC1-like intracellular cholesterol transporter 1


(Rattus norvegicus)		BDBM50371522
PNG
(CHEMBL257849)
Show SMILES COc1ccc([C@@H]2[C@H](OC(=O)N2c2ccc(F)cc2)[C@H](O)CCc2ccccc2)c(OC)c1
Show InChI InChI=1S/C26H26FNO5/c1-31-20-13-14-21(23(16-20)32-2)24-25(22(29)15-8-17-6-4-3-5-7-17)33-26(30)28(24)19-11-9-18(27)10-12-19/h3-7,9-14,16,22,24-25,29H,8,15H2,1-2H3/t22-,24-,25-/m1/s1
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Similars
Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membrane

Bioorg Med Chem Lett 18: 546-53 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.083
BindingDB Entry DOI: 10.7270/Q22F7P9P
More data for this
Ligand-Target Pair