Found 2 hits of ki for monomerid = 50380922 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50380922
(CHEMBL2016739)Show SMILES CN([C@H]1CC[C@]2(CC1)OC(=O)c1ccncc21)C(=O)Nc1cnc(cn1)-c1ccccc1 |r,wU:2.1,5.8,(11.2,-3.59,;11.2,-5.13,;9.87,-5.9,;9.87,-7.44,;8.53,-8.21,;7.19,-7.43,;7.2,-5.9,;8.53,-5.13,;7.27,-8.97,;5.83,-9.52,;5.42,-11.01,;4.86,-8.32,;3.32,-8.23,;2.62,-6.86,;3.47,-5.56,;5.01,-5.65,;5.7,-7.03,;12.53,-5.9,;12.53,-7.44,;13.86,-5.13,;15.2,-5.9,;16.52,-5.13,;17.85,-5.89,;17.86,-7.44,;16.52,-8.21,;15.19,-7.44,;19.19,-8.21,;19.19,-9.75,;20.52,-10.51,;21.85,-9.74,;21.84,-8.2,;20.51,-7.44,)| Show InChI InChI=1S/C24H23N5O3/c1-29(23(31)28-21-15-26-20(14-27-21)16-5-3-2-4-6-16)17-7-10-24(11-8-17)19-13-25-12-9-18(19)22(30)32-24/h2-6,9,12-15,17H,7-8,10-11H2,1H3,(H,27,28,31)/t17-,24+ | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes |
Bioorg Med Chem Lett 22: 2738-43 (2012)
Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50380922
(CHEMBL2016739)Show SMILES CN([C@H]1CC[C@]2(CC1)OC(=O)c1ccncc21)C(=O)Nc1cnc(cn1)-c1ccccc1 |r,wU:2.1,5.8,(11.2,-3.59,;11.2,-5.13,;9.87,-5.9,;9.87,-7.44,;8.53,-8.21,;7.19,-7.43,;7.2,-5.9,;8.53,-5.13,;7.27,-8.97,;5.83,-9.52,;5.42,-11.01,;4.86,-8.32,;3.32,-8.23,;2.62,-6.86,;3.47,-5.56,;5.01,-5.65,;5.7,-7.03,;12.53,-5.9,;12.53,-7.44,;13.86,-5.13,;15.2,-5.9,;16.52,-5.13,;17.85,-5.89,;17.86,-7.44,;16.52,-8.21,;15.19,-7.44,;19.19,-8.21,;19.19,-9.75,;20.52,-10.51,;21.85,-9.74,;21.84,-8.2,;20.51,-7.44,)| Show InChI InChI=1S/C24H23N5O3/c1-29(23(31)28-21-15-26-20(14-27-21)16-5-3-2-4-6-16)17-7-10-24(11-8-17)19-13-25-12-9-18(19)22(30)32-24/h2-6,9,12-15,17H,7-8,10-11H2,1H3,(H,27,28,31)/t17-,24+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Antagonist activity at human NPYY1 assessed as inhibition of [35S]GTPgammaS binding |
Bioorg Med Chem Lett 22: 2738-43 (2012)
Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34 |
More data for this Ligand-Target Pair | |