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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50397483   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50397483
PNG
(CHEMBL2171014)
Show SMILES CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(C)c1Cl
Show InChI InChI=1S/C26H34Cl2N4O4S/c1-18-23(27)8-9-24(25(18)28)36-21-12-16-31(17-13-21)20-10-14-32(15-11-20)26(33)29-37(34,35)22-6-4-19(5-7-22)30(2)3/h4-9,20-21H,10-17H2,1-3H3,(H,29,33)
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Article
PubMed
3.16n/an/an/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assay


Bioorg Med Chem Lett 22: 6688-93 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.124
BindingDB Entry DOI: 10.7270/Q2QF8V00
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50397483
PNG
(CHEMBL2171014)
Show SMILES CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(C)c1Cl
Show InChI InChI=1S/C26H34Cl2N4O4S/c1-18-23(27)8-9-24(25(18)28)36-21-12-16-31(17-13-21)20-10-14-32(15-11-20)26(33)29-37(34,35)22-6-4-19(5-7-22)30(2)3/h4-9,20-21H,10-17H2,1-3H3,(H,29,33)
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Article
PubMed
19.9n/an/an/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [3H]pyrilamine from human H1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 22: 6688-93 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.124
BindingDB Entry DOI: 10.7270/Q2QF8V00
More data for this
Ligand-Target Pair