Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inosine-5'-monophosphate dehydrogenase 2 (Mus musculus) | BDBM50421763 (CHEMBL2364562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against Inosine-5'-monophosphate dehydrogenase, the type of inhibition in not competitive | J Med Chem 29: 1726-31 (1986) BindingDB Entry DOI: 10.7270/Q2348MK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human)) | BDBM50421763 (CHEMBL2364562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino Curated by ChEMBL | Assay Description The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2 | J Med Chem 41: 1702-7 (1998) Article DOI: 10.1021/jm970772e BindingDB Entry DOI: 10.7270/Q23J3DNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human)) | BDBM50421763 (CHEMBL2364562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino Curated by ChEMBL | Assay Description The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2 | J Med Chem 41: 1702-7 (1998) Article DOI: 10.1021/jm970772e BindingDB Entry DOI: 10.7270/Q23J3DNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human)) | BDBM50421763 (CHEMBL2364562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino Curated by ChEMBL | Assay Description The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1 | J Med Chem 41: 1702-7 (1998) Article DOI: 10.1021/jm970772e BindingDB Entry DOI: 10.7270/Q23J3DNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human)) | BDBM50421763 (CHEMBL2364562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino Curated by ChEMBL | Assay Description The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1 | J Med Chem 41: 1702-7 (1998) Article DOI: 10.1021/jm970772e BindingDB Entry DOI: 10.7270/Q23J3DNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate dehydrogenase 1, mitochondrial (Bos taurus) | BDBM50421763 (CHEMBL2364562) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester Medical Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against bovine liver glutamate dehydrogenase (GDH) | J Med Chem 33: 1123-7 (1990) BindingDB Entry DOI: 10.7270/Q28P6131 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Sus scrofa) | BDBM50421763 (CHEMBL2364562) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester Medical Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against pig heart lactate dehydrogenase (LDH) | J Med Chem 33: 1123-7 (1990) BindingDB Entry DOI: 10.7270/Q28P6131 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alcohol dehydrogenase E/S chain (Equus caballus) | BDBM50421763 (CHEMBL2364562) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester Medical Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against horse liver Alcohol dehydrogenase (ADH) | J Med Chem 33: 1123-7 (1990) BindingDB Entry DOI: 10.7270/Q28P6131 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate dehydrogenase, cytoplasmic (Sus scrofa (pig)) | BDBM50421763 (CHEMBL2364562) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester Medical Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against pig heart cytoplasmic malate dehydrogenase (MDH) | J Med Chem 33: 1123-7 (1990) BindingDB Entry DOI: 10.7270/Q28P6131 | |||||||||||
More data for this Ligand-Target Pair |