Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM50427698 (CHEMBL2324206) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Clinic Curated by ChEMBL | Assay Description Inhibition of human recombinant IDE-mediated fluorescein-Abeta-(1-40)-Lys-biotin degradation | J Med Chem 56: 2246-55 (2013) Article DOI: 10.1021/jm301280p BindingDB Entry DOI: 10.7270/Q2DB836R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM50427698 (CHEMBL2324206) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Clinic Curated by ChEMBL | Assay Description Inhibition of human recombinant IDE-mediated FRET1 degradation | J Med Chem 56: 2246-55 (2013) Article DOI: 10.1021/jm301280p BindingDB Entry DOI: 10.7270/Q2DB836R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-degrading enzyme (Homo sapiens (Human)) | BDBM50427698 (CHEMBL2324206) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Clinic Curated by ChEMBL | Assay Description Inhibition of human recombinant IDE-mediated insulin degradation | J Med Chem 56: 2246-55 (2013) Article DOI: 10.1021/jm301280p BindingDB Entry DOI: 10.7270/Q2DB836R | |||||||||||
More data for this Ligand-Target Pair |