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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 765   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)
BDBM765
PNG
(Cyclooctylpyranonesulfonamide deriv. 8d | N-{3-[cy...)
Show SMILES Cc1cccc(c1)S(=O)(=O)Nc1cccc(c1)C(C1CC1)c1c(O)c2CCCCCCc2oc1=O
Show InChI InChI=1S/C28H31NO5S/c1-18-8-6-11-22(16-18)35(32,33)29-21-10-7-9-20(17-21)25(19-14-15-19)26-27(30)23-12-4-2-3-5-13-24(23)34-28(26)31/h6-11,16-17,19,25,29-30H,2-5,12-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
5 -46.9n/an/an/an/an/a5.022



Upjohn



Assay Description
HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...


J Med Chem 38: 4968-71 (1995)


Article DOI: 10.1021/jm00026a002
BindingDB Entry DOI: 10.7270/Q2ZP449D
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)
BDBM765
PNG
(Cyclooctylpyranonesulfonamide deriv. 8d | N-{3-[cy...)
Show SMILES Cc1cccc(c1)S(=O)(=O)Nc1cccc(c1)C(C1CC1)c1c(O)c2CCCCCCc2oc1=O
Show InChI InChI=1S/C28H31NO5S/c1-18-8-6-11-22(16-18)35(32,33)29-21-10-7-9-20(17-21)25(19-14-15-19)26-27(30)23-12-4-2-3-5-13-24(23)34-28(26)31/h6-11,16-17,19,25,29-30H,2-5,12-15H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.30 -46.8n/an/an/an/an/a5.022



Upjohn



Assay Description
HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...


J Med Chem 40: 1149-64 (1997)


Article DOI: 10.1021/jm960441m
BindingDB Entry DOI: 10.7270/Q2736P28
More data for this
Ligand-Target Pair