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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Hydroxytryptamine receptor 6 (5-HT6)' and Ligand = 'BDBM28615'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM28615
PNG
(3-methyl-2-[(1S)-1-phenylethoxy]-4-(piperidin-4-yl...)
Show SMILES C[C@H](Oc1nccc(C2CCNCC2)c1C)c1ccccc1 |r|
Show InChI InChI=1S/C19H24N2O/c1-14-18(17-8-11-20-12-9-17)10-13-21-19(14)22-15(2)16-6-4-3-5-7-16/h3-7,10,13,15,17,20H,8-9,11-12H2,1-2H3/t15-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
48.5 -41.7n/an/an/an/an/an/a25



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...


Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair