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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activating transcription factor 1' and Ligand = 'BDBM50062660'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Activating transcription factor 1


(Homo sapiens (Human))
BDBM50062660
PNG
(2-Methoxy-4-trifluoromethyl-pyrimidine-5-carboxyli...)
Show SMILES COc1ncc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(n1)C(F)(F)F
Show InChI InChI=1S/C13H8Cl2F3N3O2/c1-23-12-19-5-9(10(21-12)13(16,17)18)11(22)20-8-3-6(14)2-7(15)4-8/h2-5H,1H3,(H,20,22)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1


J Med Chem 41: 413-9 (1998)


Article DOI: 10.1021/jm970671g
BindingDB Entry DOI: 10.7270/Q2P55MMZ
More data for this
Ligand-Target Pair