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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CVF-Bb Complex' and Ligand = 'BDBM251349'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251349
PNG
(US9452990, 29)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc2cc(F)ccc2[nH]1 |r|
Show InChI InChI=1/C29H26F2N6O3/c1-39-23-14-19-25(24(31)26(23)40-2)34-29(35-27(19)32)37-11-10-36(15-22(37)16-6-4-3-5-7-16)28(38)21-13-17-12-18(30)8-9-20(17)33-21/h3-9,12-14,22,33H,10-11,15H2,1-2H3,(H2,32,34,35)/t22-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 14n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9452990 (2016)

More data for this
Ligand-Target Pair