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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CVF-Bb Complex' and Ligand = 'BDBM251451'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251451
PNG
(US9452990, 80)
Show SMILES CN[C@H](CC(=O)N1CCN(CC1)c1nc(N)c2cc(OC)c(OC)c(F)c2n1)c1ccc(F)cc1 |r|
Show InChI InChI=1/C24H28F2N6O3/c1-28-17(14-4-6-15(25)7-5-14)13-19(33)31-8-10-32(11-9-31)24-29-21-16(23(27)30-24)12-18(34-2)22(35-3)20(21)26/h4-7,12,17,28H,8-11,13H2,1-3H3,(H2,27,29,30)/t17-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/a7.425



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9452990 (2016)

More data for this
Ligand-Target Pair