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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 19A1' and Ligand = 'BDBM50357539'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50357539
PNG
(CHEMBL1915151)
Show SMILES COC(=O)[C@@H]1Cc2c(CN1C(=O)OCC=C)[nH]c1ccccc21 |r|
Show InChI InChI=1S/C17H18N2O4/c1-3-8-23-17(21)19-10-14-12(9-15(19)16(20)22-2)11-6-4-5-7-13(11)18-14/h3-7,15,18H,1,8-10H2,2H3/t15-/m0/s1
PDB
MMDB

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PC cid
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Article
PubMed
n/an/a 4.48E+4n/an/an/an/an/an/a



University of Hawai'i at Hilo

Curated by ChEMBL


Assay Description
Inhibition of aromatase after 10 mins preincubation by plate reader relative to control


Bioorg Med Chem 19: 6182-95 (2011)


Article DOI: 10.1016/j.bmc.2011.09.020
BindingDB Entry DOI: 10.7270/Q2Z89CTS
More data for this
Ligand-Target Pair