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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 (DGAT1)' and Ligand = 'BDBM50399695'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 1 (DGAT1)


(Homo sapiens (Human))
BDBM50399695
PNG
(CHEMBL2178933)
Show SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CCO)CC1 |r,wU:17.18,wD:20.22,(37.77,-23.43,;39.1,-22.65,;40.44,-23.43,;41.77,-22.65,;43.1,-23.42,;41.77,-21.12,;40.43,-20.35,;39.1,-21.11,;37.77,-20.34,;36.43,-21.11,;37.77,-18.8,;43.1,-20.35,;44.43,-21.12,;45.77,-20.35,;45.76,-18.8,;44.43,-18.04,;43.1,-18.81,;47.1,-18.03,;47.09,-16.49,;48.43,-15.72,;49.76,-16.49,;51.1,-15.72,;52.43,-16.49,;53.76,-15.72,;49.76,-18.03,;48.43,-18.8,)|
Show InChI InChI=1S/C21H27N3O2/c1-13-19(24-20(21(22)26)14(2)23-13)18-9-7-17(8-10-18)16-5-3-15(4-6-16)11-12-25/h7-10,15-16,25H,3-6,11-12H2,1-2H3,(H2,22,26)/t15-,16-
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 690n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography


J Med Chem 55: 10610-29 (2012)


Article DOI: 10.1021/jm301296t
BindingDB Entry DOI: 10.7270/Q2XD12T3
More data for this
Ligand-Target Pair