new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dopamine receptors; D2 & D4' and Ligand = 'BDBM50156966'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50156966
PNG
(CHEMBL3792803)
Show SMILES COc1cc(CN2CCO[C@H](COc3cccc(F)c3)C2)ccc1Cl |r|
Show InChI InChI=1/C19H21ClFNO3/c1-23-19-9-14(5-6-18(19)20)11-22-7-8-24-17(12-22)13-25-16-4-2-3-15(21)10-16/h2-6,9-10,17H,7-8,11-13H2,1H3/t17-/s2
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
10n/an/an/an/an/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 26: 2481-8 (2016)


BindingDB Entry DOI: 10.7270/Q2G44S5M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50156966
PNG
(CHEMBL3792803)
Show SMILES COc1cc(CN2CCO[C@H](COc3cccc(F)c3)C2)ccc1Cl |r|
Show InChI InChI=1/C19H21ClFNO3/c1-23-19-9-14(5-6-18(19)20)11-22-7-8-24-17(12-22)13-25-16-4-2-3-15(21)10-16/h2-6,9-10,17H,7-8,11-13H2,1H3/t17-/s2
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 37n/an/an/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Displacement of [3H]-Spiperone from human recombinant dopamine D4 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 26: 2481-8 (2016)


BindingDB Entry DOI: 10.7270/Q2G44S5M
More data for this
Ligand-Target Pair