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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-coupled receptor 44' and Ligand = 'BDBM124838'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM124838
PNG
(US8759386, 35)
Show SMILES CCc1c(oc2c(F)cc(F)cc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1
Show InChI InChI=1S/C25H23F2N3O4/c1-4-18-20-9-16(26)10-21(27)23(20)34-24(18)25(33)28-17-7-5-15(6-8-17)12-30-14(3)19(11-22(31)32)13(2)29-30/h5-10H,4,11-12H2,1-3H3,(H,28,33)(H,31,32)
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PC cid
PC sid
UniChem
US Patent
0.300 -54.4n/an/an/an/an/a7.425



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


US Patent US8759386 (2014)

More data for this
Ligand-Target Pair