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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminyl Cyclase' and Ligand = 'BDBM50435539'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM50435539
PNG
(CHEMBL2392786)
Show SMILES Cc1nc2ccc(NC(=S)NCCCn3cncc3C)cc2o1
Show InChI InChI=1S/C16H19N5OS/c1-11-9-17-10-21(11)7-3-6-18-16(23)20-13-4-5-14-15(8-13)22-12(2)19-14/h4-5,8-10H,3,6-7H2,1-2H3,(H2,18,20,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 329n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analys...


Bioorg Med Chem 21: 3821-30 (2013)


Article DOI: 10.1016/j.bmc.2013.04.005
BindingDB Entry DOI: 10.7270/Q2BR8TJF
More data for this
Ligand-Target Pair