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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatic Lipase (HL)' and Ligand = 'BDBM151462'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151462
PNG
(US8987314, B273)
Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)OC(C)(C)C)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C30H33N3O7S3/c1-19-16-24-25(17-23(19)21-10-12-22(13-11-21)29(35)40-30(2,3)4)41-28(33-24)26(27(34)32-14-15-43(31,38)39)42(36,37)18-20-8-6-5-7-9-20/h5-13,16-17,26H,14-15,18H2,1-4H3,(H,32,34)(H2,31,38,39)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair