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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-8 receptors, CXCR2' and Ligand = 'BDBM50236067'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50236067
PNG
((R)-3-(2-(1-(3-fluoro-5-(trifluoromethyl)phenyl)pr...)
Show SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C23H21F4N3O4/c1-4-15(11-8-12(23(25,26)27)10-13(24)9-11)28-17-18(21(33)20(17)32)29-16-7-5-6-14(19(16)31)22(34)30(2)3/h5-10,15,28-29,31H,4H2,1-3H3/t15-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
7.90n/an/an/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human CXCR2 by SPA assay


Bioorg Med Chem Lett 18: 1864-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.010
BindingDB Entry DOI: 10.7270/Q2CC10DK
More data for this
Ligand-Target Pair