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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-8 receptors, CXCR2' and Ligand = 'BDBM50248083'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50248083
PNG
((R)-(3-(4-(2,2-dimethyl-1-(5-methylfuran-2-yl)prop...)
Show SMILES Cc1ccc(o1)[C@H](Nc1nsnc1Nc1cccc(C(=O)N2CCOCC2)c1O)C(C)(C)C |r|
Show InChI InChI=1S/C23H29N5O4S/c1-14-8-9-17(32-14)19(23(2,3)4)25-21-20(26-33-27-21)24-16-7-5-6-15(18(16)29)22(30)28-10-12-31-13-11-28/h5-9,19,29H,10-13H2,1-4H3,(H,24,26)(H,25,27)/t19-/m0/s1
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Article
PubMed
1.27E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of IL8 from CXCR2 receptor (unknown origin)


Bioorg Med Chem Lett 19: 1434-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.027
BindingDB Entry DOI: 10.7270/Q2833RW1
More data for this
Ligand-Target Pair