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Found 1 hit Enz. Inhib. hit(s) with Target = 'KCNQ (Kv7) potassium channel' and Ligand = 'BDBM50395512'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
KCNQ (Kv7) potassium channel


(Homo sapiens (Human))
BDBM50395512
PNG
(CHEMBL2164057)
Show SMILES CC(C)(C(=O)Nc1ccccc1N1CCCC1)c1ccccc1
Show InChI InChI=1S/C20H24N2O/c1-20(2,16-10-4-3-5-11-16)19(23)21-17-12-6-7-13-18(17)22-14-8-9-15-22/h3-7,10-13H,8-9,14-15H2,1-2H3,(H,21,23)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay


J Med Chem 55: 6975-9 (2012)


Article DOI: 10.1021/jm300700v
More data for this
Ligand-Target Pair