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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein 1' and Ligand = 'BDBM50068384'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50068384
PNG
(CHEMBL3402345)
Show SMILES CC(C)(C)C(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F |c:7|
Show InChI InChI=1/C21H20F2N2O2S/c1-20(2,3)19(26)25-21(10-11-27-17-7-5-4-6-15(17)21)28-18(24-25)14-12-13(22)8-9-16(14)23/h4-9,12H,10-11H2,1-3H3
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of KSP in human HCT116 cells assessed as phos-histone H3 level by immunofluorescent assay


Bioorg Med Chem 23: 2424-34 (2015)


Article DOI: 10.1016/j.bmc.2015.03.052
More data for this
Ligand-Target Pair