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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Kinesin-like protein 1' and Ligand = 'BDBM50382560'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50382560
PNG
(CHEMBL2023002)
Show SMILES Cc1ccc(cc1)C(CCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25N/c1-19-13-15-22(16-14-19)23(17-8-18-24,20-9-4-2-5-10-20)21-11-6-3-7-12-21/h2-7,9-16H,8,17-18,24H2,1H3
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9.70n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...


J Med Chem 55: 1511-25 (2012)


Article DOI: 10.1021/jm201195m
BindingDB Entry DOI: 10.7270/Q2CZ386T
More data for this
Ligand-Target Pair
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50382560
PNG
(CHEMBL2023002)
Show SMILES Cc1ccc(cc1)C(CCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25N/c1-19-13-15-22(16-14-19)23(17-8-18-24,20-9-4-2-5-10-20)21-11-6-3-7-12-21/h2-7,9-16H,8,17-18,24H2,1H3
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16n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...


J Med Chem 56: 1878-93 (2013)


Article DOI: 10.1021/jm3014597
BindingDB Entry DOI: 10.7270/Q20866NN
More data for this
Ligand-Target Pair
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50382560
PNG
(CHEMBL2023002)
Show SMILES Cc1ccc(cc1)C(CCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H25N/c1-19-13-15-22(16-14-19)23(17-8-18-24,20-9-4-2-5-10-20)21-11-6-3-7-12-21/h2-7,9-16H,8,17-18,24H2,1H3
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16.4n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...


J Med Chem 55: 1511-25 (2012)


Article DOI: 10.1021/jm201195m
BindingDB Entry DOI: 10.7270/Q2CZ386T
More data for this
Ligand-Target Pair