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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein 1' and Ligand = 'BDBM50427263'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50427263
PNG
(CHEMBL2325433)
Show SMILES CC(C)c1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H29N/c1-20(2)21-11-9-16-24(19-21)25(17-10-18-26,22-12-5-3-6-13-22)23-14-7-4-8-15-23/h3-9,11-16,19-20H,10,17-18,26H2,1-2H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
6.70n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...


J Med Chem 56: 1878-93 (2013)


Article DOI: 10.1021/jm3014597
BindingDB Entry DOI: 10.7270/Q20866NN
More data for this
Ligand-Target Pair