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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein 1' and Ligand = 'BDBM50427289'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50427289
PNG
(CHEMBL2325424)
Show SMILES Cc1ccc(cc1)C(CCC(N)C(O)=O)(c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C24H25NO3/c1-17-10-12-19(13-11-17)24(15-14-22(25)23(27)28,18-6-3-2-4-7-18)20-8-5-9-21(26)16-20/h2-13,16,22,26H,14-15,25H2,1H3,(H,27,28)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
7.80n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...


J Med Chem 56: 1878-93 (2013)


Article DOI: 10.1021/jm3014597
BindingDB Entry DOI: 10.7270/Q20866NN
More data for this
Ligand-Target Pair