new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)' and Ligand = 'BDBM182717'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM182717
PNG
(US9145402, 24)
Show SMILES CNc1nc(Nc2ccc(cc2OC)N2CCOCC2)ncc1Cl
Show InChI InChI=1S/C16H20ClN5O2/c1-18-15-12(17)10-19-16(21-15)20-13-4-3-11(9-14(13)23-2)22-5-7-24-8-6-22/h3-4,9-10H,5-8H2,1-2H3,(H2,18,19,20,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...


US Patent US9145402 (2015)


BindingDB Entry DOI: 10.7270/Q2J67FQ3
More data for this
Ligand-Target Pair