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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor Edg-4' and Ligand = 'BDBM50373830'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor Edg-4


(Homo sapiens (Human))
BDBM50373830
PNG
(CHEMBL401543)
Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)Cc1ccccc1)Nc1ncnc2c(C)csc12
Show InChI InChI=1S/C21H27N5O2S2/c1-16-13-29-20-19(16)22-15-23-21(20)24-17(2)12-25-8-10-26(11-9-25)30(27,28)14-18-6-4-3-5-7-18/h3-7,13,15,17H,8-12,14H2,1-2H3,(H,22,23,24)/t17-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.86E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay


Bioorg Med Chem Lett 18: 1037-41 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8
More data for this
Ligand-Target Pair