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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor' and Ligand = 'BDBM50301100'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50301100
PNG
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)be...)
Show SMILES CCCNCc1ccc(COn2ccc(OCc3ccc(F)cc3)cc2=O)cc1
Show InChI InChI=1S/C23H25FN2O3/c1-2-12-25-15-18-3-5-20(6-4-18)17-29-26-13-11-22(14-23(26)27)28-16-19-7-9-21(24)10-8-19/h3-11,13-14,25H,2,12,15-17H2,1H3
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KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR


Bioorg Med Chem Lett 19: 5186-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.023
BindingDB Entry DOI: 10.7270/Q2G44QCG
More data for this
Ligand-Target Pair