new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melatonin receptor' and Ligand = 'BDBM50188397'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melatonin receptor


(Homo sapiens (Human))
BDBM50188397
PNG
(CHEMBL207676 | N-(2-[5-methoxy-1H-indol-3-yl]-2,2-...)
Show SMILES CCCC(=O)NCC1(CCC1)c1c[nH]c2ccc(OC)cc12
Show InChI InChI=1S/C18H24N2O2/c1-3-5-17(21)20-12-18(8-4-9-18)15-11-19-16-7-6-13(22-2)10-14(15)16/h6-7,10-11,19H,3-5,8-9,12H2,1-2H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
57.4n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]iodomelatonin from human recombinant MT2 receptor expressed in NIH3T3 cells


J Med Chem 49: 3509-19 (2006)


Article DOI: 10.1021/jm0512544
BindingDB Entry DOI: 10.7270/Q2JW8DJQ
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50188397
PNG
(CHEMBL207676 | N-(2-[5-methoxy-1H-indol-3-yl]-2,2-...)
Show SMILES CCCC(=O)NCC1(CCC1)c1c[nH]c2ccc(OC)cc12
Show InChI InChI=1S/C18H24N2O2/c1-3-5-17(21)20-12-18(8-4-9-18)15-11-19-16-7-6-13(22-2)10-14(15)16/h6-7,10-11,19H,3-5,8-9,12H2,1-2H3,(H,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
116n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]iodomelatonin from human recombinant MT1 receptor expressed in NIH3T3 cells


J Med Chem 49: 3509-19 (2006)


Article DOI: 10.1021/jm0512544
BindingDB Entry DOI: 10.7270/Q2JW8DJQ
More data for this
Ligand-Target Pair