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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4 (mGluR4)' and Ligand = 'BDBM50358184'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50358184
PNG
(CHEMBL1921954)
Show SMILES Fc1cc(ccc1NC(=O)c1ccccn1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H12FN3O5S2/c19-13-11-12(8-9-14(13)21-18(23)15-5-3-4-10-20-15)22-28(24,25)16-6-1-2-7-17(16)29(22,26)27/h1-11H,(H,21,23)
UniProtKB/SwissProt

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GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.10E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay


J Med Chem 54: 7639-47 (2011)


Article DOI: 10.1021/jm200956q
BindingDB Entry DOI: 10.7270/Q25Q4WHD
More data for this
Ligand-Target Pair