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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4 (mGluR4)' and Ligand = 'BDBM50358186'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50358186
PNG
(CHEMBL1921956)
Show SMILES O=S1(=O)N(c2ccc(NC3(CC3)c3ccccn3)cc2)S(=O)(=O)c2ccccc12
Show InChI InChI=1S/C20H17N3O4S2/c24-28(25)17-5-1-2-6-18(17)29(26,27)23(28)16-10-8-15(9-11-16)22-20(12-13-20)19-7-3-4-14-21-19/h1-11,14,22H,12-13H2
UniProtKB/SwissProt

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GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 6.40E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay


J Med Chem 54: 7639-47 (2011)


Article DOI: 10.1021/jm200956q
BindingDB Entry DOI: 10.7270/Q25Q4WHD
More data for this
Ligand-Target Pair