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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutral Endopeptidase (NEP)' and Ligand = 'BDBM50289194'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50289194
PNG
((S)-2-[(S)-4-((R)-2-Mercapto-3-phenyl-propionylami...)
Show SMILES CC(C)C[C@H](N1Cc2ccccc2C[C@H](NC(=O)[C@H](S)Cc2ccccc2)C1=O)C(O)=O
Show InChI InChI=1S/C25H30N2O4S/c1-16(2)12-21(25(30)31)27-15-19-11-7-6-10-18(19)14-20(24(27)29)26-23(28)22(32)13-17-8-4-3-5-9-17/h3-11,16,20-22,32H,12-15H2,1-2H3,(H,26,28)(H,30,31)/t20-,21-,22+/m0/s1
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MMDB

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PC cid
PC sid
UniChem
Article
0.400n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of neutral endopeptidase (NEP).


Bioorg Med Chem Lett 6: 957-962 (1996)


Article DOI: 10.1016/0960-894X(96)00149-7
BindingDB Entry DOI: 10.7270/Q2BV7GMV
More data for this
Ligand-Target Pair