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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin/mu opioid receptor' and Ligand = 'BDBM50166054'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50166054
PNG
((S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Show SMILES C[C@H]([C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O)c1ccccc1
Show InChI InChI=1S/C35H43N5O5/c1-21-17-26(41)18-22(2)27(21)20-28(36)35(45)40-16-10-15-30(40)34(44)38-29(19-24-11-6-4-7-12-24)33(43)39-31(32(37)42)23(3)25-13-8-5-9-14-25/h4-9,11-14,17-18,23,28-31,41H,10,15-16,19-20,36H2,1-3H3,(H2,37,42)(H,38,44)(H,39,43)/t23-,28-,29-,30-,31-/m0/s1
PDB

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PC cid
PC sid
UniChem
Article
PubMed
0.350n/an/an/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptor


J Med Chem 48: 3239-50 (2005)


Article DOI: 10.1021/jm049157i
BindingDB Entry DOI: 10.7270/Q28P601Q
More data for this
Ligand-Target Pair