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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 4' and Ligand = 'BDBM50085137'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4


(RAT)
BDBM50085137
PNG
(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc(cc2cccnc12)-c1ccco1
Show InChI InChI=1S/C18H11N3O3/c22-21(23)14-6-1-4-12(10-14)18-17-13(5-2-8-19-17)11-15(20-18)16-7-3-9-24-16/h1-11H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 510n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiae


J Med Chem 43: 675-82 (2000)


BindingDB Entry DOI: 10.7270/Q2N58N3G
More data for this
Ligand-Target Pair