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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50126340'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)


(Bos taurus (bovine))
BDBM50126340
PNG
(4-[(3-Cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmeth...)
Show SMILES Cn1cncc1CN(Cc1cccc(Cl)c1)c1ccc(C#N)c(c1)-c1cccc2ccccc12
Show InChI InChI=1S/C29H23ClN4/c1-33-20-32-17-26(33)19-34(18-21-6-4-9-24(30)14-21)25-13-12-23(16-31)29(15-25)28-11-5-8-22-7-2-3-10-27(22)28/h2-15,17,20H,18-19H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 0.450n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against farnesyltransferase (FTase)


Bioorg Med Chem Lett 13: 1367-71 (2003)


BindingDB Entry DOI: 10.7270/Q20K27ZP
More data for this
Ligand-Target Pair