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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Kinase C, alpha' and Ligand = 'BDBM50133251'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C, alpha


(Bos taurus (bovine))
BDBM50133251
PNG
(CHEMBL336963 | Tetradecanedioic acid 4-(2-hydroxym...)
Show SMILES CC(C)[C@@H]1C([C@@H](CO)NC1=O)c1ccc(OC(=O)CCCCCCCCCCCCC(=O)Oc2ccc([C@@H]3[C@@H](CO)NC(=O)[C@@H]3C(C)C)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C50H64N2O8/c1-31(2)45-47(39(29-53)51-49(45)57)37-25-27-41(35-21-17-15-19-33(35)37)59-43(55)23-13-11-9-7-5-6-8-10-12-14-24-44(56)60-42-28-26-38(34-20-16-18-22-36(34)42)48-40(30-54)52-50(58)46(48)32(3)4/h15-22,25-28,31-32,39-40,45-48,53-54H,5-14,23-24,29-30H2,1-4H3,(H,51,57)(H,52,58)/t39-,40-,45-,46-,47-,48?/m1/s1
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
154n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]


J Med Chem 46: 4196-204 (2003)


Article DOI: 10.1021/jm0302041
BindingDB Entry DOI: 10.7270/Q2GF0SX2
More data for this
Ligand-Target Pair