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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Kinase C' and Ligand = 'BDBM2627'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C


(Rattus norvegicus (rat))
BDBM2627
PNG
(3-(7-Amino-1-methyl-3-indolyl)-4-(1-methyl-3-indol...)
Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3c(N)cccc23)c2ccccc12 |t:4|
Show InChI InChI=1S/C22H18N4O2/c1-25-10-14(12-6-3-4-9-17(12)25)18-19(22(28)24-21(18)27)15-11-26(2)20-13(15)7-5-8-16(20)23/h3-11H,23H2,1-2H3,(H,24,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Roche Products Limited



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


J Med Chem 35: 177-84 (1992)


Article DOI: 10.1016/j.bmc.2005.03.050
BindingDB Entry DOI: 10.7270/Q2K64G8V
More data for this
Ligand-Target Pair