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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-tyrosine phosphatase 1B' and Ligand = 'BDBM50113302'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50113302
PNG
(CHEMBL420925 | N-[1-(4-Hydroxy-phenylcarbamoyl)-2-...)
Show SMILES Oc1ccc(NC(=O)C(\NC(=O)c2ccccc2)=C\c2c[nH]c3ccccc23)cc1
Show InChI InChI=1S/C24H19N3O3/c28-19-12-10-18(11-13-19)26-24(30)22(27-23(29)16-6-2-1-3-7-16)14-17-15-25-21-9-5-4-8-20(17)21/h1-15,25,28H,(H,26,30)(H,27,29)/b22-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.15E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptide


J Med Chem 45: 2213-21 (2002)


BindingDB Entry DOI: 10.7270/Q2SB46F1
More data for this
Ligand-Target Pair