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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium Channel Complex' and Ligand = 'BDBM70866'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium Channel Complex


(Homo sapiens (Human))
BDBM70866
PNG
(US9694002, 42)
Show SMILES Fc1cc(O[C@@H]2CCCN(C2)c2cc(Cl)cc(Cl)c2)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1 |r|
Show InChI InChI=1/C24H25Cl2FN2O4S/c25-15-8-16(26)10-17(9-15)29-7-1-2-18(13-29)33-23-12-22(27)21(11-20(23)14-3-4-14)24(30)28-34(31,32)19-5-6-19/h8-12,14,18-19H,1-7,13H2,(H,28,30)/t18-/s2
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.10n/an/an/an/a7.425



GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent


Assay Description
Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...


US Patent US9694002 (2017)


BindingDB Entry DOI: 10.7270/Q24B2ZFG
More data for this
Ligand-Target Pair