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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type I' and Ligand = 'BDBM50304875'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50304875
PNG
(4-(1H-indol-5-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Show SMILES Cn1c(c(-c2ccc3[nH]ccc3c2)c(=O)n1C)-c1ccc2nccnc2c1
Show InChI InChI=1S/C21H17N5O/c1-25-20(15-4-6-17-18(12-15)24-10-9-23-17)19(21(27)26(25)2)14-3-5-16-13(11-14)7-8-22-16/h3-12,22H,1-2H3
PDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.12E+3n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 326-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.108
More data for this
Ligand-Target Pair