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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription factor AP-1' and Ligand = 'BDBM50213935'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))
BDBM50213935
PNG
((12aS,13R)-2,3,6,7-tetramethoxy-9,10,11,12,12a,13-...)
Show SMILES COc1cc2c3CN4CCC[C@H]4[C@H](O)c3c3cc(OC)c(OC)cc3c2cc1OC
Show InChI InChI=1S/C24H27NO5/c1-27-19-8-13-14-9-20(28-2)22(30-4)11-16(14)23-17(15(13)10-21(19)29-3)12-25-7-5-6-18(25)24(23)26/h8-11,18,24,26H,5-7,12H2,1-4H3/t18-,24-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>300n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assay


Bioorg Med Chem Lett 17: 4338-42 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.021
BindingDB Entry DOI: 10.7270/Q2HD7VBW
More data for this
Ligand-Target Pair