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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)' and Ligand = 'BDBM50161538'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50161538
PNG
(4-(3-Hydroxy-4-methyl-phenylamino)-5-propyl-pyrrol...)
Show SMILES CCCc1c(cn2ncnc(Nc3ccc(C)c(O)c3)c12)C(=O)OCC
Show InChI InChI=1S/C19H22N4O3/c1-4-6-14-15(19(25)26-5-2)10-23-17(14)18(20-11-21-23)22-13-8-7-12(3)16(24)9-13/h7-11,24H,4-6H2,1-3H3,(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory concentration against Vascular endothelial growth factor receptor 2


Bioorg Med Chem Lett 15: 1429-33 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.079
BindingDB Entry DOI: 10.7270/Q2JS9PZR
More data for this
Ligand-Target Pair