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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)' and Ligand = 'BDBM50215756'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50215756
PNG
(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Show SMILES COc1ccc2nc([nH]c2c1)-c1n[nH]cc1C=Cc1cnccc1C |w:17.20|
Show InChI InChI=1S/C19H17N5O/c1-12-7-8-20-10-13(12)3-4-14-11-21-24-18(14)19-22-16-6-5-15(25-2)9-17(16)23-19/h3-11H,1-2H3,(H,21,24)(H,22,23)
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Article
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n/an/a 760n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development L.L.C.

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2


Bioorg Med Chem Lett 17: 4557-61 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.092
BindingDB Entry DOI: 10.7270/Q2DB81JD
More data for this
Ligand-Target Pair